The most obvious examples of this are his final signings while in charge the Gunners, with most becoming regulars for the Premier League side.
His signings were not all successes though, with some players failing to make an appearance for the Gunners in any competition.
Here, Mirror Football analyses Wenger’s last 10 signings and what affect they have had on Arsenal’s future.
Transfer fee: £40.5million
After joining from Borussia Monengladbach in 2016, Xhaka quickly established himself as a key member of Arsenal’s midfield.
His tough-tackling displays saw Xhaka rise to become Arsenal captain, though Unai Emery did strip him of that honour in 2019.
But the midfielder bounced back from that disappointment, becoming a virtual ever-present under Mikel Arteta, starting 21 Premier League games so far this season.
With Thomas Partey now at the club though, Xhaka will have to keep up his recent good form if he is to retain his place in the side.
Transfer fee: £36.9million
Mustafi was brought in to help shore up the Arsenal defence, but the move failed to pay off, with the German finding himself sidelined by Arteta.
The centre-back made 151 appearances for the Gunners, but never looked completely solid at the back.
That led to Arteta terminating Mustafi’s contract in January, with the centre-back subsequently returning to his home league of the Bundesliga with Schalke.
Transfer fee: £18million
Perez spent just a single season at Arsenal and it was no surprise when he joined Deportivo la Coruna on loan at the end of the campaign.
The Spanish striker had been fairly prolific in La Liga, but it took him until January 2017 to register a goal in the Premier League.
In fact, Perez scored just seven times for the Gunners in all competitions and was sent back to Spain ahead of the next season.
Transfer fee: £2.7million
One of Wenger’s best signings, Holding joined the Gunners from Bolton for just £2.7m in the summer of 2016.
His opening seasons at the club were blighted by injury, but he has since established himself as one of Arteta’s first-choice centre-backs.
He has started 22 Premier League matches so far this campaign and was handed the captain’s armband for the defeat to Everton in December.
Holding has been solid at the back, helping the Gunners to keep eight clean sheets so far this campaign, while he has yet to make an error leading to a goal.
Transfer fee: £3.6million
It would be difficult to find a player who had a smaller impact on a club than Asano did on Arsenal after his move from Sanfrecce Hiroshima.
The Japanese winger failed to make an appearance for Arsenal during his three years at the Emirates.
Instead, he was loaned out to German clubs Stuttgart and Hannover, where he similarly failed to really have an impact in front of goal.
Asano joined Partizan Belgrade for a nominal fee in the summer transfer window of 2019.
Transfer fee: Free
Kolasinac was undoubtedly a bargain as Arsenal were able to secure his services on a free transfer in 2017.
The Bosnian quickly established himself as a fans favourite at the Emirates and was the Gunners’ first-choice left-back heading into the season.
But the emergence of Kieran Tierney severely limited Kolasinac’s game time, with the Scot becoming a virtual ever-present under Mikel Arteta.
The subsequent lack of minutes for Kolasinac led to him departing Arsenal for Schalke on loan in January, though he will still have a year left on his contract when he returns from Germany.
Transfer fee: £47.7million
After scoring 28 goals in 30 Ligue 1 games for Lyon in the 2016/2017 season, Lacazette was heralded as the man to become Arsenal’s leading striker.
But since his move to the Emirates, the Frenchman has not quite hit the heights expected of an elite forward, with his highest Premier League goal tally being 14.
Mikel Arteta has appeared to prefer to play Pierre-Emerick Aubameyang as his leading striker in recent months, though Lacazette was handed a start against Leicester last week.
Though he scored a penalty against the Foxes, rumours of a possible departure have intensified, with Lacazette having only 18 months left to run on his deal.
Transfer fee: £1.8million
Mavropanos is undoubtedly viewed as one for the future by Arsenal, having made the majority of his appearances in Premier League 2.
Though he has made a handful of outings for the senior side, he has been loaned out to Stuttgart and Nuremberg in recent seasons.
He made 11 appearances for the latter in the 2 Bundesliga, before making the step up to Germany’s top-flight this season.
The 23-year-old has become a key member of a backline which has helped newly-promoted Stuttgart to concede just two goals in their last three matches.
Transfer fee: Swap for Alexis Sanchez
Many consider Mkhitaryan to be a flop after his spells at Manchester United and Arsenal.
The Armenian midfielder’s Emirates career had started so well, claiming three assists on his first start for the Gunners as they thrashed Everton 5-1.
He then scored six goals and recorded four more assists the following season, but was loaned out to Roma by Unai Emery.
And with Emile Smith Rowe breaking through, Mikel Arteta clearly did not believe Mkhitaryan was the answer to his side’s struggles to find a number 10, so terminated his contract.
Transfer fee: £57.3million
Aubameyang has been one of Wenger’s best signings since joining from Borussia Dortmund in January 2018.
He has scored 22 goals for two successive seasons before the current campaign and has established himself as Mikel Arteta’s main striker.
Frequently spoken of as one of the best strikers in the Premier League, Aubameyang has experienced a downturn in form this campaign, but should be Arsenal’s leading man for many years to come.