Covaxin single-dose for survivor may be as effective as both for uninfected

According to a pilot study by ICMR (Indian Council for Medical Research) a single dose of Bharat Biotech’s Covaxin in people who have been infected with the virus has a response that is similar to that provided by two doses of the vaccine in those without any history of the infection, a report by TOI has said.

This is based on preliminary data and ICMR has said that these findings need to be confirmed with larger cohorts of data.

“This study offers evidence in support of public health-oriented and immunologically sustained vaccine strategies. If our preliminary findings are confirmed in large population studies, a single dose of BBV152 vaccine may be recommended to previously confirmed SARS-CoV-2 infected individuals so that the naïve individuals could attain the larger benefit of a limited vaccine supply,” says the short paper with the findings of the study published in the Indian Journal of Medical Research.

Regardless, the authors of the study have reiterated that taking both doses of the vaccine is still recommended.

This study conducted by the ICMR involved frontline and healthcare workers that were examined for e SARS-CoV-2–specific antibody responses after day zero (baseline, before vaccination), Day 28 (month 1) and Day 56 post-first dose (month 2) of Covaxin.


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